The acoustic startle reflex in stiff–man syndrome

Joseph Y. Matsumoto, John N. Caviness, Kathleen M. McEvoy

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


We studied the EMG response to loud noise in eight patients with stiff-man syndrome (SMS). Audiogenic muscle jerks originated in the acoustic startle reflex. Patients demonstrated excessive, poorly habituating motor activity predominately in axial and leg muscles. Exaggerated startle in SMS probably reflects segmental hyperexcitability of axial and lumbar spinal motor neurons.

Original languageEnglish (US)
Pages (from-to)1952-1957
Number of pages6
Issue number10
StatePublished - Oct 1994

ASJC Scopus subject areas

  • Clinical Neurology


Dive into the research topics of 'The acoustic startle reflex in stiff–man syndrome'. Together they form a unique fingerprint.

Cite this