Temperature and brain protection in cardiac surgery

George Djaiani, Harish Ramakrishna, Alina M. Grigore

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


It is well known and has been clearly demonstrated that temperature plays a significant role in cerebral physiology and physiopathology, particularly in the setting of cardiac surgery with cardiopulmonary bypass (CPB). The human central nervous system (CNS) receives about 15% of the resting cardiac output and consumes about 20% of the oxygen required by the body at rest. The brain, which accounts for 2% of the total body weight, has an oxygen consumption of about 3.5 mL-1·100 g-1·min-1. This high metabolic rate mandates a high blood flow; therefore, cerebral blood flow (CBF) (Fig. 13.1) is of paramount importance and is normally under metabolic, neural, myogenic, and chemical control.1

Original languageEnglish (US)
Title of host publicationBrain Protection in Cardiac Surgery
PublisherSpringer London
Number of pages17
ISBN (Print)9781849962926
StatePublished - 2011

ASJC Scopus subject areas

  • Medicine(all)


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