Targeting tumor-associated myeloid cells for cancer immunotherapy

Hong Qin, Guowei Wei, Dongho Gwak, Zhenyuan Dong, Ailian Xiong, Larry W. Kwak

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Tumor-associated myeloid cells undermine the therapeutic efficacy of cancer immunotherapy by their inhibitory properties on immune effector cells. Development of therapeutic agents to deplete suppressive myeloid cells in tumor microenvironment requires identification of cell-specific targets. A competitive phage display technique on live cells paves the way to discovery of such a target.

Original languageEnglish (US)
Pages (from-to)1-3
Number of pages3
Issue number3
StatePublished - 2015


  • Immunosuppression
  • Immunotherapy
  • Myeloid-derived suppressor cells
  • Peptibody
  • Tumor microenvironment

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Oncology


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