Takotsubo Cardiomyopathy: Definition and Clinical Profile

Matthew R. Summers, Abhiram Prasad

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations


Takotsubo cardiomyopathy (TTC) is an increasingly recognized, reversible cardiomyopathy with a clinical presentation that mimics an acute coronary syndrome but without evidence of obstructive coronary lesions. Typical presentation involves chest pain and/or dyspnea, transient ST-segment elevation on the electrocardiogram, and a modest increase in cardiac troponin. Cardiac imaging demonstrates wall-motion abnormalities that extend beyond the territory of a single epicardial coronary artery, and the absence of obstructive coronary lesions. Supportive treatment leads to spontaneous, rapid recovery of ventricular function, but about 10% of patients have recurrent events. This article reviews the defining features and clinical profile of TTC.

Original languageEnglish (US)
Pages (from-to)111-122
Number of pages12
JournalHeart Failure Clinics
Issue number2
StatePublished - Apr 2013


  • Apical ballooning syndrome
  • Stress cardiomyopathy
  • Takotsubo cardiomyopathy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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