Systemic chemotherapy in patients with renal failure

Lishan Bekele, Marieberta Vidal Vazquez, Alex A. Adjei

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The administration of systemic chemotherapy to patients with moderate-to-severe organ impairment remains a challenge. In renal failure, guidelines for dose adjustments exist for very few chemotherapy agents. Subsequently, oncologists typically withhold treatment with systemic chemotherapy for patients with severe renal dysfunction. We present the case of a patient with metastatic transitional cell carcinoma of the bladder and renal failure who underwent successful systemic chemotherapy with paclitaxel and carboplatin. The data on systemic chemotherapy in patients with severe renal dysfunction are reviewed.

Original languageEnglish (US)
Pages (from-to)382-384
Number of pages3
JournalAmerican Journal of Clinical Oncology: Cancer Clinical Trials
Issue number4
StatePublished - 2001


  • Bladder cancer
  • Carboplatin
  • Chemotherapy
  • Paclitaxel
  • Renal failure

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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