Synthesis of deuterated β‐carotene

H. Robert Bergen, James A. Olson

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The synthesis of 10,10′,19,19,19,19′,19′,19′‐2H8‐β‐carotene is described. The double condensation (C15+C10+C15=C40) of the Wittig salt of 9,9,9,10‐2H4‐β‐ionylidene ethanol with the symmetrical C10 dial 2,7‐dimethyl‐2,4,6‐octatrienedial led directly to 2H8‐β‐carotene. The symmetrical labelling pattern of this deuterated β‐carotene will function as a tracer for the study of β‐carotene metabolism in humans.

Original languageEnglish (US)
Pages (from-to)783-788
Number of pages6
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Issue number7
StatePublished - Jul 1989


  • 10,10′,19,19,19,19′,19′,19′‐H‐β‐carotene
  • 9,9,9,10‐H‐β‐ionylidene ethanol
  • 9,9,9,10‐H‐β‐ionylideneethyl triphenyl phosphonium bromide
  • Deuterated β‐carotene
  • carotenoid synthesis

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry


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