Synthesis and characterization of pH/temperature-sensitive hydrogels based on chitosan derivative

Akhilesh Pandey; Ippeita Dan; Troels Z. Kristiansen; Norinobu M. Watanabe; Jesper Voldby; Eriko Kajikawa; Roya Khosravi-Far; Blagoy Blagoev; Matthias Mann

doi:10.1007/s002890200008

Synthesis and characterization of pH/temperature-sensitive hydrogels based on chitosan derivative

Akhilesh Pandey, Ippeita Dan, Troels Z. Kristiansen, Norinobu M. Watanabe, Jesper Voldby, Eriko Kajikawa, Roya Khosravi-Far, Blagoy Blagoev, Matthias Mann

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

A series of pH/temperature-sensitive hydrogels composed of maleilated chitosan (MC) and N-isopropylacrylamide (NIPAAm) were prepared and characterized with respect to their swelling behaviors, change of lower critical solution temperature (LCST). These hydrogels showed broad pH-sensitivities below 32 °C, but above that temperature exhibited sharp pH-dependent phase transition behaviors which depended on the content of MC in the hydrogels. The change of ratio of NIPAAm to MC in weight did not affect LCST significantly, while it affected equilibrium water content (EWC) at high pH region. The hydrogels also exhibited a typical of reversibility depending on temperature and pH.

Original language	English (US)
Pages (from-to)	451-456
Number of pages	6
Journal	Polymer Bulletin
Volume	47
Issue number	5
DOIs	https://doi.org/10.1007/s002890200008
State	Published - Jan 1 2002

ASJC Scopus subject areas

Chemistry(all)
Condensed Matter Physics
Polymers and Plastics
Materials Chemistry

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10.1007/s002890200008

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title = "Synthesis and characterization of pH/temperature-sensitive hydrogels based on chitosan derivative",

abstract = "A series of pH/temperature-sensitive hydrogels composed of maleilated chitosan (MC) and N-isopropylacrylamide (NIPAAm) were prepared and characterized with respect to their swelling behaviors, change of lower critical solution temperature (LCST). These hydrogels showed broad pH-sensitivities below 32 °C, but above that temperature exhibited sharp pH-dependent phase transition behaviors which depended on the content of MC in the hydrogels. The change of ratio of NIPAAm to MC in weight did not affect LCST significantly, while it affected equilibrium water content (EWC) at high pH region. The hydrogels also exhibited a typical of reversibility depending on temperature and pH.",

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T1 - Synthesis and characterization of pH/temperature-sensitive hydrogels based on chitosan derivative

AU - Pandey, Akhilesh

AU - Dan, Ippeita

AU - Kristiansen, Troels Z.

AU - Watanabe, Norinobu M.

AU - Voldby, Jesper

AU - Kajikawa, Eriko

AU - Khosravi-Far, Roya

AU - Blagoev, Blagoy

AU - Mann, Matthias

PY - 2002/1/1

Y1 - 2002/1/1

N2 - A series of pH/temperature-sensitive hydrogels composed of maleilated chitosan (MC) and N-isopropylacrylamide (NIPAAm) were prepared and characterized with respect to their swelling behaviors, change of lower critical solution temperature (LCST). These hydrogels showed broad pH-sensitivities below 32 °C, but above that temperature exhibited sharp pH-dependent phase transition behaviors which depended on the content of MC in the hydrogels. The change of ratio of NIPAAm to MC in weight did not affect LCST significantly, while it affected equilibrium water content (EWC) at high pH region. The hydrogels also exhibited a typical of reversibility depending on temperature and pH.

AB - A series of pH/temperature-sensitive hydrogels composed of maleilated chitosan (MC) and N-isopropylacrylamide (NIPAAm) were prepared and characterized with respect to their swelling behaviors, change of lower critical solution temperature (LCST). These hydrogels showed broad pH-sensitivities below 32 °C, but above that temperature exhibited sharp pH-dependent phase transition behaviors which depended on the content of MC in the hydrogels. The change of ratio of NIPAAm to MC in weight did not affect LCST significantly, while it affected equilibrium water content (EWC) at high pH region. The hydrogels also exhibited a typical of reversibility depending on temperature and pH.

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Synthesis and characterization of pH/temperature-sensitive hydrogels based on chitosan derivative

Abstract

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