Summary of the update session on clinical neurotoxicity studies

Teeda Pinyavat, David O. Warner, Randall P. Flick, Mary Ellen McCann, Dean B. Andropoulos, Danquig Hu, Jeffrey W. Sall, Marisa N. Spann, Caleb Ing

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


During the Fifth Pediatric Anesthesia Neurodevelopmental Assessment Symposium, experts and stakeholders met to present and discuss recent advances made in the study of neurodevelopmental outcomes after exposure to anesthetic drugs in infants and children. This article summarizes the update of 5 ongoing clinical studies: General Anesthesia compared to Spinal Anesthesia, Toxicity of Remifentanil and Dexmedetomidine, Mayo Anesthesia Safety in Kids, the University of California San Francisco human cohort study, and Columbia University Medical Center Neonatal Magnetic Resonance Imaging study. The purpose of this summary is to discuss the contributions and limitations of these studies, how they fit into the published literature, and what questions remain to be answered.

Original languageEnglish (US)
Pages (from-to)356-360
Number of pages5
JournalJournal of Neurosurgical Anesthesiology
Issue number4
StatePublished - Sep 24 2016


  • Anesthesia
  • Behavior
  • Clinical research
  • Cognition
  • Neurodevelopment
  • Pediatric

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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