Standardized Definition of Structural Valve Degeneration for Surgical and Transcatheter Bioprosthetic Aortic Valves

Danny Dvir, Thierry Bourguignon, Catherine M. Otto, Rebecca T. Hahn, Raphael Rosenhek, John G. Webb, Hendrik Treede, Maurice E. Sarano, Ted Feldman, Harindra C. Wijeysundera, Yan Topilsky, Michel Aupart, Michael J. Reardon, G. Burkhard Mackensen, Wilson Y. Szeto, Ran Kornowski, James S. Gammie, Ajit P. Yoganathan, Yaron Arbel, Michael A. BorgerMatheus Simonato, Mark Reisman, Raj R. Makkar, Alexandre Abizaid, James M. McCabe, Gry Dahle, Gabriel S. Aldea, Jonathon Leipsic, Philippe Pibarot, Neil E. Moat, Michael J. Mack, A. Pieter Kappetein, Martin B. Leon

Research output: Contribution to journalArticlepeer-review

146 Scopus citations


Bioprostheses are prone to structural valve degeneration, resulting in limited long-term durability. A significant challenge when comparing the durability of different types of bioprostheses is the lack of a standardized terminology for the definition of a degenerated valve. This issue becomes especially important when we try to compare the degeneration rate of surgically inserted and transcatheter bioprosthetic valves. This document, by the VIVID (Valve-in-Valve International Data), proposes practical and standardized definitions of valve degeneration and provides recommendations for the timing of clinical and imaging follow-up assessments accordingly. Its goal is to improve the quality of research and clinical care for patients with deteriorated bioprostheses by providing objective and strict criteria that can be utilized in future clinical trials. We hope that the adoption of these criteria by both the cardiological and surgical communities will lead to improved comparability and interpretation of durability analyses.

Original languageEnglish (US)
Pages (from-to)388-399
Number of pages12
Issue number4
StatePublished - Jan 23 2018


  • durability
  • echocardiographic criteria
  • reintervention
  • reoperation
  • transcatheter
  • valve deterioration

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


Dive into the research topics of 'Standardized Definition of Structural Valve Degeneration for Surgical and Transcatheter Bioprosthetic Aortic Valves'. Together they form a unique fingerprint.

Cite this