Stage I squamous cell cancer of the vulva

J. F. Magrina, M. J. Webb, T. A. Gaffey, R. E. Symmonds

Research output: Contribution to journalArticlepeer-review

84 Scopus citations


A review of 106 patients with Stage I squamous cell cancer of the vulva treated at the Mayo Clinic from 1950 through 1975 is presented. Microinvasive lesions (5 mm penetration or less) were present in 96 patients (91%); invasive lesions (more than 5 mm penetration) were diagnosed in 10 (9%). Inguinal node involvement was present in nine patients (8.4%); one of these also had pelvic node involvement. Recurrence developed in 13 patients (12%). Four patients experienced inguinal node metastasis after initial surgical therapy. The incidence of positive nodes among patients with lesions invading the stroma for 3 mm or less was 3%. Thus, individualization for inguinal lymphadenectomy may be possible according to the age and condition of the patient when the depth of invasion is 3 mm or less.

Original languageEnglish (US)
Pages (from-to)453-459
Number of pages7
JournalAmerican journal of obstetrics and gynecology
Issue number4
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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