TY - JOUR
T1 - Species of Propionibacterium and Propionibacterium acnes phylotypes associated with orthopedic implants
AU - Fernandez Sampedro, Marta
AU - Piper, Kerryl E.
AU - McDowell, Andrew
AU - Patrick, Sheila
AU - Mandrekar, Jayawant N.
AU - Rouse, Mark S.
AU - Steckelberg, James M.
AU - Patel, Robin
N1 - Funding Information:
Supported by Marques de Valdecilla Foundation (Cantabria, Spain), and the Arthritis Foundation.
Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2009/6
Y1 - 2009/6
N2 - Propionibacterium sp. is commonly isolated in association with orthopedic implants, either as a pathogen or a colonizer. Microbial characteristics that indicate whether the isolated species is a likely cause of orthopedic implant infection versus a colonizing agent would be clinically useful. We performed a prospective trial to determine the species of Propionibacterium and the phylotype (IA, IB, II, III) of Propionibacterium acnes isolated from the surface of removed orthopedic implants, and we correlated these findings with the presence or absence of infection. P. acnes represented 61 of 62 isolates. P. acnes type I was more commonly isolated than was type II (62% versus 38%, respectively), whether associated with infection or not. P. acnes type III was not detected. There was no clear association between types I and II P. acnes and infection or colonization of failed orthopedic implants (P = 0.75), however type IB strains were more frequently isolated than type IA from infected prosthese.
AB - Propionibacterium sp. is commonly isolated in association with orthopedic implants, either as a pathogen or a colonizer. Microbial characteristics that indicate whether the isolated species is a likely cause of orthopedic implant infection versus a colonizing agent would be clinically useful. We performed a prospective trial to determine the species of Propionibacterium and the phylotype (IA, IB, II, III) of Propionibacterium acnes isolated from the surface of removed orthopedic implants, and we correlated these findings with the presence or absence of infection. P. acnes represented 61 of 62 isolates. P. acnes type I was more commonly isolated than was type II (62% versus 38%, respectively), whether associated with infection or not. P. acnes type III was not detected. There was no clear association between types I and II P. acnes and infection or colonization of failed orthopedic implants (P = 0.75), however type IB strains were more frequently isolated than type IA from infected prosthese.
KW - Propionibacterium acnes
KW - Propionibacterium spp.
KW - orthopedic implants
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U2 - 10.1016/j.diagmicrobio.2009.01.024
DO - 10.1016/j.diagmicrobio.2009.01.024
M3 - Article
C2 - 19505429
AN - SCOPUS:66549099985
SN - 0732-8893
VL - 64
SP - 138
EP - 145
JO - Diagnostic Microbiology and Infectious Disease
JF - Diagnostic Microbiology and Infectious Disease
IS - 2
ER -