Spatio-temporal directional filtering for improved inversion of MR elastography images

A. Manduca, D. S. Lake, S. A. Kruse, R. L. Ehman

Research output: Contribution to journalArticlepeer-review

227 Scopus citations


Dynamic magnetic resonance elastography can visualize and measure propagating shear waves in tissue-like materials subjected to harmonic mechanical excitation. This allows the calculation of local values of material parameters such as shear modulus and attenuation. Various inversion algorithms to perform such calculations have been proposed, but they are sensitive to areas of low displacement amplitude (and hence low SNR) that result from interference patterns due to reflection and refraction. A spatio-temporal directional filter applied as a pre-processing step can separate interfering waves so they can be processed separately. Weighted combinations of inversions from such directionally separated data sets can significantly improve reconstructions of shear modulus and attenuation.

Original languageEnglish (US)
Pages (from-to)465-473
Number of pages9
JournalMedical Image Analysis
Issue number4
StatePublished - Dec 2003


  • Elasticity
  • Elastography
  • Inversion algorithms
  • Shear modulus
  • Tissue characterization

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Computer Vision and Pattern Recognition
  • Health Informatics
  • Computer Graphics and Computer-Aided Design


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