TY - JOUR
T1 - Spanish cross-cultural adaptation and validation of the National Institutes of Health Stroke Scale
AU - Domínguez, Raúl
AU - Vila, José F.
AU - Augustovski, Federico
AU - Irazola, Vilma
AU - Castillo, Pablo R.
AU - Escalante, Roberto Rotta
AU - Brott, Thomas G.
AU - Meschia, James F.
N1 - Funding Information:
This study was supported by an independent grant from Aventis Pharma, Argentina.
PY - 2006/4
Y1 - 2006/4
N2 - OBJECTIVES: To adapt and validate a Spanish-language version (SV) of the National institutes of Health Stroke Scale (NIHSS) to facilitate its use in Spanish-speaking contexts. PATIENTS AND METHODS: The methods recommended by the International Quality of Life Assessment Project were followed. Two forward translations and 1 back translation of the NIHSS were developed to ensure lingual and cultural equivalence. A final revised SV-NIHSS was administered by 8 physicians to patients with stroke in 3 clinics in Buenos Aires, Argentina, from September 2003 to December 2003. RESULTS: The study included 102 patients (mean ± SD age, 73.3±6.5 years; 56% women) with stroke (86% ischemic). The SV-NIHSS mean baseline score was 9.78±7.04. Interrater reliability was independently evaluated for 98 patients, showing a high agreement: κ, 0.77 to 0.99 for the 15 items; interrater correlation coefficient, 0.991 (95% confidence interval, 0.987-0.994). Intrarater reliability was excellent: κ, 0.86 to 1.00 for the 15 items; mean intrarater correlation coefficient, 0.994 (95% confidence interval, 0.991-0.996). Construct validity was also adequate; the SV-NIHSS had a negative correlation with baseline Glasgow Coma Scale (Spearman coefficient = -0.574, P<.001) and with Barthel Index at 3 months (Spearman coefficient = -0.658, P<.001). Patients with different Rankin scores at 3 months also had significantly different baseline SV-NIHSS scores, from a mean of 4.29±2.21 for Rankin score of 0 to a mean of 29.40±3.97 for Rankin score of 6 (P<.001). CONCLUSION: This study shows that a Spanish-language version of the NIHSS developed with internationally recommended methods is reliable and valid when applied in a Spanish-speaking setting.
AB - OBJECTIVES: To adapt and validate a Spanish-language version (SV) of the National institutes of Health Stroke Scale (NIHSS) to facilitate its use in Spanish-speaking contexts. PATIENTS AND METHODS: The methods recommended by the International Quality of Life Assessment Project were followed. Two forward translations and 1 back translation of the NIHSS were developed to ensure lingual and cultural equivalence. A final revised SV-NIHSS was administered by 8 physicians to patients with stroke in 3 clinics in Buenos Aires, Argentina, from September 2003 to December 2003. RESULTS: The study included 102 patients (mean ± SD age, 73.3±6.5 years; 56% women) with stroke (86% ischemic). The SV-NIHSS mean baseline score was 9.78±7.04. Interrater reliability was independently evaluated for 98 patients, showing a high agreement: κ, 0.77 to 0.99 for the 15 items; interrater correlation coefficient, 0.991 (95% confidence interval, 0.987-0.994). Intrarater reliability was excellent: κ, 0.86 to 1.00 for the 15 items; mean intrarater correlation coefficient, 0.994 (95% confidence interval, 0.991-0.996). Construct validity was also adequate; the SV-NIHSS had a negative correlation with baseline Glasgow Coma Scale (Spearman coefficient = -0.574, P<.001) and with Barthel Index at 3 months (Spearman coefficient = -0.658, P<.001). Patients with different Rankin scores at 3 months also had significantly different baseline SV-NIHSS scores, from a mean of 4.29±2.21 for Rankin score of 0 to a mean of 29.40±3.97 for Rankin score of 6 (P<.001). CONCLUSION: This study shows that a Spanish-language version of the NIHSS developed with internationally recommended methods is reliable and valid when applied in a Spanish-speaking setting.
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U2 - 10.4065/81.4.476
DO - 10.4065/81.4.476
M3 - Article
C2 - 16610567
AN - SCOPUS:33645661213
SN - 0025-6196
VL - 81
SP - 476
EP - 480
JO - Mayo Clinic proceedings
JF - Mayo Clinic proceedings
IS - 4
ER -