Soft tissue response to silicones

S. E. Gabriel

Research output: Chapter in Book/Report/Conference proceedingChapter


Although the term ’silicone’ refers to a group of organic silicone compounds, the one most commonly used in medicine is composed of a polymer known as dimethypolysiloxane (DMPS). In silicone gel the polymer is cross-linked; the more cross-linking, the more solid is the gel. Liquid silicone consists of glucose-linked DMPS polymer chains. Silicones first became commercially available in 1943, with the first subdermal implantation of silicone occurring in the late 1940s [1-3]. Silicones have since been developed for a wide variety of medical applications, most notably in joint and breast prostheses.

Original languageEnglish (US)
Title of host publicationHandbook of Biomaterial Properties, Second Edition
PublisherSpringer New York
Number of pages14
ISBN (Electronic)9781493933051
ISBN (Print)9781493933037
StatePublished - Jan 1 2016

ASJC Scopus subject areas

  • Engineering(all)
  • Materials Science(all)
  • Biochemistry, Genetics and Molecular Biology(all)


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