Smoking-Related—Interstitial Lung Disease

Teng Moua, Anja C. Roden, Vincent Cottin

Research output: Chapter in Book/Report/Conference proceedingChapter


This article highlights the smoking-related interstitial lung diseases including respiratory bronchiolitis-associated interstitial lung disease (RB-ILD), desquamative interstitial pneumonia (DIP), pulmonary Langerhans cell histiocytosis (PLCH), combined pulmonary fibrosis and emphysema (CPFE) and smoking-related interstitial fibrosis (SRIF). All share cigarette smoking as a likely cause of presenting disease, of which characteristic clinical findings, radiologic features, and histopathology will be reviewed. For a majority of the smoking-related interstitial lung diseases, smoking cessation is a vital first step to reversing disease course or slowing progression, along with directed anti-inflammatory or immunosuppressant therapy.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Respiratory Medicine, Second Edition
Number of pages15
ISBN (Electronic)9780081027240
ISBN (Print)9780081027233
StatePublished - Jan 1 2021


  • Cigarette smoke
  • Combined pulmonary fibrosis and emphysema
  • Desquamative interstitial lung disease
  • Interstitial lung disease
  • Langerhans cell histiocytosis
  • Respiratory bronchiolitis
  • Smoking-related interstitial fibrosis

ASJC Scopus subject areas

  • General Medicine


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