Smoking-Related Interstitial Lung Diseases

Research output: Chapter in Book/Report/Conference proceedingChapter


Cigarette smoke is recognized as the primary causative agent of certain interstitial lung diseases (ILDs), namely respiratory bronchiolitis-associated ILD, desquamative interstitial pneumonia, and pulmonary Langerhans cell histiocytosis. Cigarette smoking is also responsible for some cases of acute eosinophilic pneumonia and appears to be a risk factor for the development of idiopathic pulmonary fibrosis and rheumatoid arthritis-associated ILD. Some smokers with emphysema develop a superimposed fibrotic process resulting in combined pulmonary fibrosis and emphysema syndrome associated with preserved lung volumes. Smoking cessation should occupy a pivotal role in the management of all smokers with these diffuse lung diseases.

Original languageEnglish (US)
Title of host publicationInterstitial Lung Disease
PublisherElsevier Inc.
Number of pages15
ISBN (Electronic)9780323480253
ISBN (Print)9780323480246
StatePublished - Mar 6 2017


  • Acute eosinophilic pneumonia
  • Desquamative interstitial pneumonia
  • Fibrosis
  • Interstitial lung disease
  • Pulmonary Langerhans cell histiocytosis
  • Respiratory bronchiolitis
  • Smoking

ASJC Scopus subject areas

  • General Medicine


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