Singling Out Chromosome Gains in Tumor Evolution

Ryan M. Naylor, Jan M. van Deursen

Research output: Contribution to journalShort surveypeer-review


In this issue of Cancer Cell, Sheltzer et al. shed new light on Theodor Boveri's century-old hypothesis by demonstrating that aneuploidy characterized by single-chromosome gains acts to suppress tumorigenesis and that aneuploidy itself is a nidus for genomic instability.

Original languageEnglish (US)
Pages (from-to)165-166
Number of pages2
JournalCancer cell
Issue number2
StatePublished - Feb 13 2017

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research


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