Shrinking lung syndrome in pregnancy complicated by antiphospholipid antibody syndrome

Monika Meena, Christopher C. Destephano, William J. Watson, Brian C. Brost

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Background: Shrinking lung syndrome is characterized by pulmonary compromise secondary to unilateral or bilateral paralysis of the diaphragm. Case: Shrinking lung syndrome was diagnosed in a patient with antiphospholipid syndrome after a cesarean delivery at 28 4/7 weeks of gestation. Signs and symptoms included unexplained right-side chest pain, dyspnea, tachypnea, and absent breath sounds at the right base of the lungs. After initiation of corticosteroids, her symptoms resolved. Conclusion: Although seen in association with systemic lupus erythematosus, shrinking lung syndrome has not been described with antiphospholipid syndrome or during pregnancy. Diagnosis and awareness are important because treatment with moderate- to high-dose corticosteroids appears to improve the clinical outcome.

Original languageEnglish (US)
Pages (from-to)506-508
Number of pages3
JournalObstetrics and gynecology
Issue number2 PART 2
StatePublished - Feb 1 2011

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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