Self-limited epilepsies in childhood

Identification of epilepsy electroclinical syndromes is important to determine potential etiologies, preferred treatments, possible comorbidities, and expected outcomes. However, atypical features can make classification challenging but does not exclude classification. Childhood epilepsy with centrotemporal spikes is a self-limited and pharmaco-responsive epilepsy. However, there are many overlapping features with childhood-onset epileptic encephalopathies, such as Landau-Kleffner syndrome and epileptic encephalopathy with continuous spike-and-wave during sleep syndromes. Therefore, a careful history and additional evaluation are warranted for children who present with atypical features.