Secreted ORF8 induces monocytic pro-inflammatory cytokines through NLRP3 pathways in patients with severe COVID-19

Xiaosheng Wu, Michelle K. Manske, Gordon J. Ruan, Taylor L. Witter, Kevin E. Nowakowski, Jithma P. Abeykoon, Xinyi Tang, Yue Yu, Kimberly A. Gwin, Annie Wu, Vanessa Taupin, Vaishali Bhardwaj, Jonas Paludo, Surendra Dasari, Haidong Dong, Stephen M. Ansell, Andrew D. Badley, Matthew J. Schellenberg, Thomas E. Witzig

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Medicine & Life Sciences