Screening for lung cancer: The US studies

David E. Midthun, James R. Jett

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Efforts in lung cancer screening with chest X-ray (CXR) and sputum cytology in the 1970s and 1980s were negative. In the ensuing decade, the early lung cancer action project (ELCAP), and the Mayo screening study showed the promise of low-dose CT. These and other studies led to the National lung screening study (NLST), which showed definitively that low-dose spiral computed tomography had a measurable impact on mortality and could be justified as a tool for lung cancer screening. This review examines the results of past and recent studies of lung cancer screening. J. Surg. Oncol. 2013 108:275-279.

Original languageEnglish (US)
Pages (from-to)275-279
Number of pages5
JournalJournal of Surgical Oncology
Issue number5
StatePublished - Oct 1 2013


  • CT screening
  • lung cancer
  • mortality reduction
  • nodule evaluation
  • randomized trial

ASJC Scopus subject areas

  • Surgery
  • Oncology


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