Rosai-dorfman disease: Manifestations outside of the head and neck

Winnie A. Mar, H. Yu Jonathan, Martha Gracia Knuttinen, Jeanne M. Horowitz, Odile David, Andrew Wilbur, Christine O. Menias

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


OBJECTIVE. Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. We review less common imaging findings outside the head and neck. CONCLUSION. The imaging manifestations of RDD overlap with a variety of neoplastic and nonneoplastic conditions. Confirmation of an RDD diagnosis is based on specific histologic features. Radiologic assessment is used to rule out multifocality on initial workup and to evaluate treatment response.

Original languageEnglish (US)
Pages (from-to)721-732
Number of pages12
JournalAmerican Journal of Roentgenology
Issue number4
StatePublished - Apr 2017


  • Abdominal
  • Extranodal
  • Histiocytosis
  • Rosai-Dorfman disease
  • Thoracic

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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