Rhabdomyolysis after transnasal repair of anterior basal encephalocele

Jamie J. Van Gompel, Yasin A. Khan, Eric L. Bloomfield, John F. Pallanch, John L.D. Atkinson

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Background: Postoperative Rhabdomyolysis (RM) is rare after neurosurgical procedures. Furthermore, it has not been observed after transnasal approaches. The authors report a case of idiopathic RM occurring after transnasal resection of a sincipital encephalocele. Case Description: A 32-year-old woman underwent a transnasal resection of a sincipital encephalocele after 6 years of intermittent clear nasal drainage. Postoperatively, she experienced severe back pain, peripheral neuropathy, associated with a markedly elevated creatinine kinase, and severe RM. The patient was treated with hydration and forced urine alkalization and treated symptomatically for her pain and neuropathy. She ultimately made a full recovery without complication. Conclusion: Rhabdomyolysis is a rare but known complication of neurosurgical procedures. We report the first known case report of RM after a transnasal procedure. Furthermore, a review of documented postneurosurgical cases of RM is presented and reveals that the causes and risk factors for this complication after neurosurgery are similar to those in other surgical subspecialties.

Original languageEnglish (US)
Pages (from-to)757-760
Number of pages4
JournalSurgical Neurology
Issue number6
StatePublished - Dec 2009


  • Encephalocele
  • Rhabdomyolysis
  • Transnasal

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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