Abstract
Growing understanding of the finely orchestrated and integrated mechanisms governing sleep and wakefulness allow for new insights into sleep disorders and their pharmacological treatments. While sleep related conditions are many and diverse, this chapter focuses on the common ailments of insomnia and circadian rhythm disorders. We provide a brief overview of these conditions followed by a review of current pathophysiologic understandings for these conditions, which provide context to the subsequent medication review. While an in-depth review of the pharmacologic options is provided, section summaries and tables are included to allow for ease of accessibility and retrieval of the information.
Original language | English (US) |
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Title of host publication | Comprehensive Pharmacology |
Publisher | Elsevier |
Pages | 149-178 |
Number of pages | 30 |
Volume | 3 |
ISBN (Electronic) | 9780128204726 |
DOIs | |
State | Published - Jan 1 2022 |
Keywords
- Advanced sleep-wake rhythm disorder
- Circadian rhythm disorders
- Delayed sleep-wake phase disorder
- Insomnia
- Irregular sleep-wake rhythm disorder
- Jet lag disorder
- Management
- Medication
- Non-24h sleep-wake rhythm disorder
- Shift work disorder
ASJC Scopus subject areas
- General Pharmacology, Toxicology and Pharmaceutics
- General Medicine