Review of Select Sleep Medicine Pharmacology: Treatments of Insomnia and Circadian Rhythm Sleep-Wake Disorders

Kimberly Johnson, Meghna P. Mansukhani, Bhanu Prakash Kolla

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Growing understanding of the finely orchestrated and integrated mechanisms governing sleep and wakefulness allow for new insights into sleep disorders and their pharmacological treatments. While sleep related conditions are many and diverse, this chapter focuses on the common ailments of insomnia and circadian rhythm disorders. We provide a brief overview of these conditions followed by a review of current pathophysiologic understandings for these conditions, which provide context to the subsequent medication review. While an in-depth review of the pharmacologic options is provided, section summaries and tables are included to allow for ease of accessibility and retrieval of the information.

Original languageEnglish (US)
Title of host publicationComprehensive Pharmacology
PublisherElsevier
Pages149-178
Number of pages30
Volume3
ISBN (Electronic)9780128204726
DOIs
StatePublished - Jan 1 2022

Keywords

  • Advanced sleep-wake rhythm disorder
  • Circadian rhythm disorders
  • Delayed sleep-wake phase disorder
  • Insomnia
  • Irregular sleep-wake rhythm disorder
  • Jet lag disorder
  • Management
  • Medication
  • Non-24h sleep-wake rhythm disorder
  • Shift work disorder

ASJC Scopus subject areas

  • General Pharmacology, Toxicology and Pharmaceutics
  • General Medicine

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