Resurgence of Eating Disorders with Olanzapine

Kelly L. Wu, Amanda K. Lorenz, Kelly J. Christensen, Molly A. Feely, Elise C. Carey, Jacob J. Strand

Research output: Contribution to journalReview articlepeer-review


Background: Olanzapine is commonly utilized in palliative care for the treatment of nausea, and a known side effect of olanzapine is increased appetite. Olanzapine is also known to cause re-emergence of eating disorders (EDs) in patients utilizing olanzapine for its antipsychotic effects. It is unclear to what extent this may also occur in patients with serious/life-limiting illness. Methods and Results: We present a case of a 70-year-old female with recurrent ovarian cancer and a history of bulimia nervosa (BN) that developed resurgence of her BN after initiation of olanzapine for cancer-associated nausea. Her BN resolved with reducing the dose of olanzapine. Conclusion: It is important to recognize that recurrence of EDs can occur when using olanzapine in the palliative care setting.

Original languageEnglish (US)
Pages (from-to)231-233
Number of pages3
JournalJournal of Palliative Medicine
Issue number2
StatePublished - Feb 2019


  • feeding and eating disorders
  • nausea
  • palliative

ASJC Scopus subject areas

  • General Nursing
  • Anesthesiology and Pain Medicine


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