TY - JOUR
T1 - Respiratory syncytial virus pneumonitis-induced diffuse alveolar damage in an autologous bone marrow transplant recipient
AU - Markovic, Svetomir N.
AU - Adlakha, Arun
AU - Smith, Thomas F.
AU - Walker, Randall C.
PY - 1998
Y1 - 1998
N2 - A 24-year-old woman with recurrent Hodgkin's lymphoma, stage IIB nodular sclerosing type, underwent an autologous bone marrow transplantation. Forty- five days after transplantation, an upper respiratory tract infection developed that progressed to respiratory distress necessitating mechanical ventilation. An open-lung biopsy demonstrated diffuse alveolar damage. After an extensive search for the cause of the respiratory compromise, we detected respiratory syncytial virus in a bronchoalveolar lavage specimen. The patient was immediately treated with aerosolized ribavirin and intravenous immunoglobulin; her symptoms resolved, and she was extubated 4 days after initiation of therapy.
AB - A 24-year-old woman with recurrent Hodgkin's lymphoma, stage IIB nodular sclerosing type, underwent an autologous bone marrow transplantation. Forty- five days after transplantation, an upper respiratory tract infection developed that progressed to respiratory distress necessitating mechanical ventilation. An open-lung biopsy demonstrated diffuse alveolar damage. After an extensive search for the cause of the respiratory compromise, we detected respiratory syncytial virus in a bronchoalveolar lavage specimen. The patient was immediately treated with aerosolized ribavirin and intravenous immunoglobulin; her symptoms resolved, and she was extubated 4 days after initiation of therapy.
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U2 - 10.1016/S0025-6196(11)63648-3
DO - 10.1016/S0025-6196(11)63648-3
M3 - Article
C2 - 9472999
AN - SCOPUS:0031934383
SN - 0025-6196
VL - 73
SP - 153
EP - 156
JO - Mayo Clinic proceedings
JF - Mayo Clinic proceedings
IS - 2
ER -