TY - JOUR
T1 - Resilience
T2 - Biological Basis and Clinical Significance — A Perspective Report from the International Conference on Frailty and Sarcopenia Research (ICFSR) Task Force
AU - Cesari, Matteo
AU - Azzolino, D.
AU - LeBrasseur, N. K.
AU - Whitson, H.
AU - Rooks, D.
AU - Sourdet, S.
AU - Angioni, D.
AU - Fielding, R. A.
AU - Vellas, B.
AU - Rolland, Y.
AU - Andrieu, Sandrine
AU - Leheudre, Mylène Aubertin
AU - Barcons, Nuria
AU - Beliën, Ann
AU - de Souto Barreto, Philipe
AU - Delannoy, Carla
AU - John, Groarke
AU - Robledo, Luis Miguel Gutierrez
AU - Hwee, Darren
AU - Mariani, Jean
AU - Reshma, Merchant
AU - Morley, John
AU - Pereira, Suzette
AU - Erin, Quann
AU - Michelle, Rossulek
AU - Rueda, Ricardo
AU - Tarasenko, Lisa
AU - Tourette, Cendrine
AU - Van Maanen, Rob
AU - Waters, Debra L.
N1 - Publisher Copyright:
© 2022, The Author(s).
PY - 2022/10
Y1 - 2022/10
N2 - The Resilience is a construct receiving growing attention from the scientific community in geriatrics and gerontology. Older adults show extremely heterogeneous (and often unpredictable) responses to stressors. Such heterogeneity can (at least partly) be explained by differences in resilience (i.e., the capacity of the organism to cope with stressors). The International Conference on Frailty and Sarcopenia Research (ICFSR) Task Force met in Boston (MA,USA) on April 20, 2022 to discuss the biological and clinical significance of resilience in older adults. The identification of persons with low resilience and the prompt intervention in this at-risk population may be critical to develop and implement preventive strategies against adverse events. Unfortunately, to date, it is still challenging to capture resilience, especially due to its dynamic nature encompassing biological, clinical, subjective, and socioeconomic factors. Opportunities to dynamically measure resilience were discussed during the ICFSR Task Force meeting, emphasizing potential biomarkers and areas of intervention. This article reports the results of the meeting and may serve to support future actions in the field.
AB - The Resilience is a construct receiving growing attention from the scientific community in geriatrics and gerontology. Older adults show extremely heterogeneous (and often unpredictable) responses to stressors. Such heterogeneity can (at least partly) be explained by differences in resilience (i.e., the capacity of the organism to cope with stressors). The International Conference on Frailty and Sarcopenia Research (ICFSR) Task Force met in Boston (MA,USA) on April 20, 2022 to discuss the biological and clinical significance of resilience in older adults. The identification of persons with low resilience and the prompt intervention in this at-risk population may be critical to develop and implement preventive strategies against adverse events. Unfortunately, to date, it is still challenging to capture resilience, especially due to its dynamic nature encompassing biological, clinical, subjective, and socioeconomic factors. Opportunities to dynamically measure resilience were discussed during the ICFSR Task Force meeting, emphasizing potential biomarkers and areas of intervention. This article reports the results of the meeting and may serve to support future actions in the field.
KW - Aging
KW - biomarkers
KW - geroscience
KW - older adults
KW - translational research
UR - http://www.scopus.com/inward/record.url?scp=85140357411&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85140357411&partnerID=8YFLogxK
U2 - 10.14283/jfa.2022.62
DO - 10.14283/jfa.2022.62
M3 - Article
C2 - 36346720
AN - SCOPUS:85140357411
SN - 2260-1341
VL - 11
SP - 342
EP - 347
JO - The Journal of frailty & aging
JF - The Journal of frailty & aging
IS - 4
ER -