Renovascular hypertension.

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Renovascular disease, particularly when associated with atherosclerosis, is a common cofactor in accelerating hypertension and deteriorating renal function. With increased longevity and effective antihypertensive medications, the prevalence of vascular lesions affecting renal viability is increasing, possibly accounting for 15% of end-stage renal disease. Renal vascular lesions alter renin release and multiple associated mechanisms related to adrenergic and vascular regulation. Several new diagnostic modalities, including captopril renography, duplex ultrasonography, and magnetic resonance angiography, are being applied for noninvasive diagnosis. Advances in interventional radiologic procedures, including endovascular stents and surgical revascularization, offer the potential for both improved blood pressure management and salvage of renal function. Optimal management of renovascular disease depends on careful assessment of the progression of each patient and associated risk of intervention.

Original languageEnglish (US)
Pages (from-to)775-783
Number of pages9
JournalCurrent opinion in nephrology and hypertension
Issue number5
StatePublished - Sep 1993

ASJC Scopus subject areas

  • Internal Medicine
  • Nephrology


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