TY - JOUR
T1 - Refractory eosinophilic cystitis controlled with low-dose cyclosporine therapy
T2 - A case report
AU - Adeleye, Olufunmilola
AU - Trickett, John S.
AU - Wright, Benjamin L.
AU - Khan, Aqsa
N1 - Publisher Copyright:
© 2021
PY - 2021/11
Y1 - 2021/11
N2 - Eosinophilic cystitis (EC) is a rare disease of the bladder with no clear inciting etiology, pathogenesis, or standard treatment. We present the case of a 78-year-old woman with a three-year history of refractory EC with symptoms characterized by urinary frequency, gross hematuria, dysuria, and suprapubic pain. Despite treatment with a silver nitrate instillation, antibiotics, alpha-1 blockers, antihistamines, antimuscarinics, beta-3 agonists, and intravesical steroid injections, her symptoms persisted. She was then trialed on systemic therapies including prednisone, montelukast, and cyclosporine. Upon follow-up after initiation of therapy with low-dose cyclosporine she had an excellent response, both symptomatically and anatomically via cystoscopy.
AB - Eosinophilic cystitis (EC) is a rare disease of the bladder with no clear inciting etiology, pathogenesis, or standard treatment. We present the case of a 78-year-old woman with a three-year history of refractory EC with symptoms characterized by urinary frequency, gross hematuria, dysuria, and suprapubic pain. Despite treatment with a silver nitrate instillation, antibiotics, alpha-1 blockers, antihistamines, antimuscarinics, beta-3 agonists, and intravesical steroid injections, her symptoms persisted. She was then trialed on systemic therapies including prednisone, montelukast, and cyclosporine. Upon follow-up after initiation of therapy with low-dose cyclosporine she had an excellent response, both symptomatically and anatomically via cystoscopy.
KW - Cyclosporine
KW - Eosinophilic cystitis
UR - http://www.scopus.com/inward/record.url?scp=85114170663&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85114170663&partnerID=8YFLogxK
U2 - 10.1016/j.eucr.2021.101829
DO - 10.1016/j.eucr.2021.101829
M3 - Article
AN - SCOPUS:85114170663
SN - 2214-4420
VL - 39
JO - Urology Case Reports
JF - Urology Case Reports
M1 - 101829
ER -