Recurrent spontaneous coronary artery dissection in the United States

Chayakrit Krittanawong, Anirudh Kumar, Hafeez Ul Hassan Virk, Zhen Wang, Kipp W. Johnson, Bing Yue, Deepak L. Bhatt

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Background: Recurrent spontaneous coronary artery dissection (SCAD) is believed to be infrequent. Predictors of recurrent SCAD are poorly characterized. Methods: We evaluated the incidence, clinical characteristics, and predictors of recurrent SCAD using data from the Nationwide Readmissions Database from January 1, 2010, to December 30, 2016. Results: Among 1836 SCAD patients admitted with the primary diagnosis of SCAD (61.9% female, mean age 56.1 ± 14.5, 72.9% <65 years of age), 495 patients (26.9%) had recurrent SCAD within 1 year (74.0% female, 74% <65 years of age). Multivariable analysis showed that female sex (OR 2.09; 95% CI 1.49–2.95; p < 0.001) was an independent predictor of recurrent SCAD within 1 year. Conclusions: Recurrent SCAD is frequent and should be considered in younger females with a history of SCAD. Further research is needed to investigate the mechanistic links between female sex and recurrent SCAD.

Original languageEnglish (US)
Pages (from-to)34-37
Number of pages4
JournalInternational Journal of Cardiology
StatePublished - Feb 15 2020


  • Recurrent spontaneous coronary artery dissection
  • SCAD
  • Spontaneous coronary artery dissection

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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