Recurrent glioblastoma multiforme: Advances in treatment and promising drug candidates

Lijo Simpson, Evanthia Galanis

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations


Recurrent glioblastoma multiforme is a lethal disease with currently available treatment options having a limited impact on outcome. In this article, current and novel therapeutic approaches in the treatment of recurrent glioblastoma multiforme, including chemotherapy, targeted molecular agents, virotherapy/gene therapy and immunotherapy and challenges in developing novel therapeutic agents for glioblastoma multiforme will be discussed.

Original languageEnglish (US)
Pages (from-to)1593-1607
Number of pages15
JournalExpert review of anticancer therapy
Issue number11
StatePublished - Nov 2006


  • Chemotherapy
  • Gene therapy
  • Glioblastoma multiforme
  • Immunotherapy
  • Recurrence
  • Small molecule cell cycle inhibitors

ASJC Scopus subject areas

  • Oncology
  • Pharmacology (medical)


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