Radiological imaging of teratological fetuses: what can we learn?

Lucas L. Boer, A. N. Schepens-Franke, J. J.A. van Asten, D. G.H. Bosboom, K. Kamphuis-van Ulzen, T. L. Kozicz, D. J. Ruiter, R. J. Oostra, W. M. Klein

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


Objectives: To determine the advantages of radiological imaging of a collection of full-term teratological fetuses in order to increase their scientific and educational value. Background: Anatomical museums around the world exhibit full-term teratological fetuses. Unfortunately, these museums are regularly considered as “morbid cabinets”. Detailed dysmorphological information concerning the exhibited specimens is often lacking. Moreover, fetuses with severe and complex congenital anomalies are frequently diagnosed incompletely, incorrectly or not at all. Methods: In order to verify diagnoses and to enrich their educational and scientific value, we imaged 41 out of the 72 teratological specimens present in the collection of our Anatomy and Pathology Museum in Nijmegen (The Netherlands) by means of magnetic resonance imaging (MRI) and computed tomography (CT). Additionally, contemporary dysmorphological insights and 3D models are implemented in the teratology education of medical students and residents. Conclusions: Full-term teratological fetuses have become increasingly rare and deserve a prominent place in every anatomical museum; they are suitable for contemporary teratological research and education. Modern radiological techniques markedly enhance their scientific and didactic value.

Original languageEnglish (US)
Pages (from-to)301-310
Number of pages10
JournalInsights into Imaging
Issue number3
StatePublished - Jun 1 2017


  • Computed tomography
  • Congenital anomaly
  • Education
  • Magnetic resonance imaging
  • Teratology

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Radiological imaging of teratological fetuses: what can we learn?'. Together they form a unique fingerprint.

Cite this