Quantitative assessment of pulmonary perfusion with dynamic contrast- enhanced MRI

Hiroto Hatabu, Eiji Tadamura, David L. Levin, Qun Chen, Wei Li, Ducksoo Kim, Pottumarthi V. Prasad, Robert R. Edelman

Research output: Contribution to journalArticlepeer-review

159 Scopus citations


The feasibility of qualitative assessment of pulmonary perfusion using dynamic contrast enhanced MRI with ultra-short TE has recently been demonstrated. In the current study, quantitative analysis was attempted based on the indicator dilution principle using a pig model of pulmonary embolism. The results were compared with the absolute pulmonary perfusion obtained with colored microspheres. The inverse of apparent mean transit time (1/τ(app)), distribution volume (V), and V/τ(app) were correlated well with the absolute lung perfusion. This study demonstrates that MR has the potential to evaluate pulmonary perfusion quantitatively.

Original languageEnglish (US)
Pages (from-to)1033-1038
Number of pages6
JournalMagnetic Resonance in Medicine
Issue number6
StatePublished - 1999


  • Lung, perfusion
  • Magnetic resonance
  • Pulmonary artery

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Quantitative assessment of pulmonary perfusion with dynamic contrast- enhanced MRI'. Together they form a unique fingerprint.

Cite this