Pulmonary manifestations of inflammatory bowel disease: Case presentations and review

Benjamin Basseri, Pedram Enayati, Alberto Marchevsky, Konstantinos A. Papadakis

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Inflammatory bowel disease (IBD) is associated with a number of extraintestinal manifestations that may involve most organ systems. Extraintestinal manifestations are more common in Crohn disease (CD) and may include rheumatologic, ocular, dermatologic, biliary and pulmonary manifestations. The most common pulmonary manifestations of IBD are drug-induced lung disease. Other manifestations include parenchymal disease, pleuritis and overlap syndromes. We present a case series of 7 patients with non-infectious pulmonary manifestations of IBD, which included cryptogenic organizing pneumonia, usual interstitial pneumonitis (UIP), Langerhan's granulomatosis, and eosinophilic pneumonia. Concurrent extraintestinal manifestations present in these patients included arthralgia, iritis, and pyoderma gangrenosum. In most patients the development of pulmonary disease parallels that of the intestinal disease activity, extraintestinal manifestations and concurrent use of 5-ASA medications.

Original languageEnglish (US)
Pages (from-to)390-397
Number of pages8
JournalJournal of Crohn's and Colitis
Issue number4
StatePublished - Oct 2010


  • 5-ASA
  • Crohn's disease
  • Inflammatory bowel disease (IBD)
  • Pulmonary manifestations
  • Ulcerative colitis

ASJC Scopus subject areas

  • Gastroenterology


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