TY - JOUR
T1 - Pulmonary Limitations in Heart Failure
AU - Cundrle, Ivan
AU - Olson, Lyle J.
AU - Johnson, Bruce D.
N1 - Funding Information:
Funding: Dr I. Cundrle is supported by Czech Republic Ministry of Health (grant NV18-06-00216); National Program of Sustainability II (MEYS CR)(project no. LQ1605), and by the project FNUSA-ICRC [CZ.1.05/1.1.00/02.0123 (OP VaVpI)]. Most of the funding for Dr B.D. Johnson's laboratory relative to this article was from NIH grant HL71478.
Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/6
Y1 - 2019/6
N2 - The heart and lungs are intimately linked. Hence, impaired function of one organ may lead to changes in the other. Accordingly, heart failure is associated with airway obstruction, loss of lung volume, impaired gas exchange, and abnormal ventilatory control. Cardiopulmonary exercise testing is an excellent tool for evaluation of gas exchange and ventilatory control. Indeed, many parameters routinely measured during cardiopulmonary exercise testing, including the level of minute ventilation per unit of carbon dioxide production and the presence of exercise oscillatory ventilation, have been found to be strongly associated with prognosis in patients with heart failure.
AB - The heart and lungs are intimately linked. Hence, impaired function of one organ may lead to changes in the other. Accordingly, heart failure is associated with airway obstruction, loss of lung volume, impaired gas exchange, and abnormal ventilatory control. Cardiopulmonary exercise testing is an excellent tool for evaluation of gas exchange and ventilatory control. Indeed, many parameters routinely measured during cardiopulmonary exercise testing, including the level of minute ventilation per unit of carbon dioxide production and the presence of exercise oscillatory ventilation, have been found to be strongly associated with prognosis in patients with heart failure.
KW - Cardiopulmonary exercise testing
KW - Heart failure
KW - Ventilatory efficiency
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U2 - 10.1016/j.ccm.2019.02.010
DO - 10.1016/j.ccm.2019.02.010
M3 - Review article
C2 - 31078220
AN - SCOPUS:85065177817
SN - 0272-5231
VL - 40
SP - 439
EP - 448
JO - Clinics in Chest Medicine
JF - Clinics in Chest Medicine
IS - 2
ER -