Pulmonary Langerhans cell histiocytosis

David Levin, Thomas Hartman

Research output: Chapter in Book/Report/Conference proceedingChapter


Imaging description The classic CT appearance of pulmonary Langerhans cell histiocytosis (PLCH) is a combination of cysts and small nodules [1, 2]. Cysts are the most common finding and nodules are almost always seen in conjunction with cysts. The cysts spare the lung bases (Figures 12.1–12.4) and frequently demonstrate irregular shapes. Cyst walls can range from relatively thick to barely perceptible. The pulmonary nodules are typically 1–5 mm in diameter and also spare the bases. Nodules are typically more numerous in the early stages of the disease (Figure 12.1) while cysts predominate in later stages (Figures 12.2–12.4). Importance The diagnosis of PLCH can typically be made solely on the basis of the CT findings. Smoking cessation can result in resolution of the disease.

Original languageEnglish (US)
Title of host publicationPearls and Pitfalls in Thoracic Imaging
Subtitle of host publicationVariants and Other Difficult Diagnoses
PublisherCambridge University Press
Number of pages4
ISBN (Electronic)9780511977701
ISBN (Print)9780521119078
StatePublished - Jan 1 2011

ASJC Scopus subject areas

  • General Medicine


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