Propofol Versus Midazolam/Fentanyl Sedation for Colonoscopy in the Elderly Patient Population

Pamela Lovett, Victoria Gómez, David O. Hodge, Beth Ladlie

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Purpose Despite current literature, data on the most effective sedation and best patient outcomes are insufficient for providing recovery time recommendations for elderly patients undergoing colonoscopy with sedation. We sought to identify the best sedation practice for shorter recovery times. Therefore, a study was conducted to examine recovery times among patients older than 65 years undergoing elective colonoscopy with intravenous sedation with either propofol or the combination of midazolam/fentanyl. Design A retrospective descriptive, exploratory design was used. Methods We retrospectively reviewed data from patients older than 65 years undergoing outpatient elective colonoscopy at our institution between January and December 2013. Recovery times were evaluated for those administered intravenous propofol or a combination of midazolam/fentanyl. Patient demographics and sedation medications were obtained from patient records. A modified Aldrete score greater than 8 was required for discharge. Recovery time was defined as the time from procedure completion to a modified Aldrete score greater than 8. Findings Propofol sedation was associated with longer recovery times compared with sedation with a combination of midazolam and fentanyl (mean: 50 minutes versus 31 minutes, P <.001). Conclusions Propofol sedation was not associated with shorter recovery times. Further studies are needed to validate these findings.

Original languageEnglish (US)
Pages (from-to)210-214
Number of pages5
JournalJournal of Perianesthesia Nursing
Issue number3
StatePublished - Jun 2017


  • colonoscopy
  • elderly
  • sedation

ASJC Scopus subject areas

  • Medical–Surgical


Dive into the research topics of 'Propofol Versus Midazolam/Fentanyl Sedation for Colonoscopy in the Elderly Patient Population'. Together they form a unique fingerprint.

Cite this