Prolonged shedding of pandemic influenza A (H1N1) 2009 virus in a pancreas-after-kidney transplant recipient

Jackrapong Bruminhent; Paul J. Deziel; Jason T. Wotton; Matthew J. Binnicker; Raymund R. Razonable

doi:10.1016/j.jcv.2014.07.004

Prolonged shedding of pandemic influenza A (H1N1) 2009 virus in a pancreas-after-kidney transplant recipient

Jackrapong Bruminhent, Paul J. Deziel, Jason T. Wotton, Matthew J. Binnicker, Raymund R. Razonable

Infectious Diseases

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Prolonged shedding of influenza virus has been reported in immunocompromised patients. Delayed viral clearance may contribute to antiviral resistance and nosocomial transmission. We report a case of a pancreas-after-kidney transplant recipient who had detectable pandemic influenza A virus for 12 months. Pyrosequencing analysis detected the H275Y mutation, which is associated with resistance to oseltamivir.

Original language	English (US)
Pages (from-to)	302-304
Number of pages	3
Journal	Journal of Clinical Virology
Volume	61
Issue number	2
DOIs	https://doi.org/10.1016/j.jcv.2014.07.004
State	Published - 2014

Keywords

Immunocompromised
Influenza
Oseltamivir
Shedding
Transmission
Transplant

ASJC Scopus subject areas

Virology
Infectious Diseases

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10.1016/j.jcv.2014.07.004

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title = "Prolonged shedding of pandemic influenza A (H1N1) 2009 virus in a pancreas-after-kidney transplant recipient",

abstract = "Prolonged shedding of influenza virus has been reported in immunocompromised patients. Delayed viral clearance may contribute to antiviral resistance and nosocomial transmission. We report a case of a pancreas-after-kidney transplant recipient who had detectable pandemic influenza A virus for 12 months. Pyrosequencing analysis detected the H275Y mutation, which is associated with resistance to oseltamivir.",

keywords = "Immunocompromised, Influenza, Oseltamivir, Shedding, Transmission, Transplant",

author = "Jackrapong Bruminhent and Deziel, {Paul J.} and Wotton, {Jason T.} and Binnicker, {Matthew J.} and Razonable, {Raymund R.}",

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AU - Bruminhent, Jackrapong

AU - Deziel, Paul J.

AU - Wotton, Jason T.

AU - Binnicker, Matthew J.

AU - Razonable, Raymund R.

PY - 2014

Y1 - 2014

N2 - Prolonged shedding of influenza virus has been reported in immunocompromised patients. Delayed viral clearance may contribute to antiviral resistance and nosocomial transmission. We report a case of a pancreas-after-kidney transplant recipient who had detectable pandemic influenza A virus for 12 months. Pyrosequencing analysis detected the H275Y mutation, which is associated with resistance to oseltamivir.

AB - Prolonged shedding of influenza virus has been reported in immunocompromised patients. Delayed viral clearance may contribute to antiviral resistance and nosocomial transmission. We report a case of a pancreas-after-kidney transplant recipient who had detectable pandemic influenza A virus for 12 months. Pyrosequencing analysis detected the H275Y mutation, which is associated with resistance to oseltamivir.

KW - Immunocompromised

KW - Influenza

KW - Oseltamivir

KW - Shedding

KW - Transmission

KW - Transplant

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ER -

Prolonged shedding of pandemic influenza A (H1N1) 2009 virus in a pancreas-after-kidney transplant recipient

Abstract

Keywords

ASJC Scopus subject areas

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