Progressive multifocal leukoencephalopathy demonstrating contrast enhancement on MRI and uptake of thallium-201: A case report

J. D. Port; S. Miseljic; R. R. Lee; S. Z. Ali; T. L. Nicol; W. Royal; B. B. Chin

doi:10.1007/s002340050862

Progressive multifocal leukoencephalopathy demonstrating contrast enhancement on MRI and uptake of thallium-201: A case report

J. D. Port, S. Miseljic, R. R. Lee, S. Z. Ali, T. L. Nicol, W. Royal, B. B. Chin

Radiology

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21 Scopus citations

Abstract

We describe a patient with AIDS who presented with focal neurological symptoms, and who had contrast-enhancing brain lesions on MRI which demonstrated increased thallium-201 uptake on SPECT. These findings were consistent with lymphoma; however, brain biopsy established a diagnosis of progressive multifocal leukoencephalopathy (PML). To our knowledge, this is the first reported case of PML with increased thallium-201 uptake on brain SPECT.

Original language	English (US)
Pages (from-to)	895-898
Number of pages	4
Journal	Neuroradiology
Volume	41
Issue number	12
DOIs	https://doi.org/10.1007/s002340050862
State	Published - Dec 1 1999

Keywords

Acquired immunodeficiency syndrome
Magnetic resonance imaging
Progressive multifocal leukoencephalopathy
Single-photon emission tomography

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Clinical Neurology
Cardiology and Cardiovascular Medicine

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10.1007/s002340050862

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abstract = "We describe a patient with AIDS who presented with focal neurological symptoms, and who had contrast-enhancing brain lesions on MRI which demonstrated increased thallium-201 uptake on SPECT. These findings were consistent with lymphoma; however, brain biopsy established a diagnosis of progressive multifocal leukoencephalopathy (PML). To our knowledge, this is the first reported case of PML with increased thallium-201 uptake on brain SPECT.",

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AU - Lee, R. R.

AU - Ali, S. Z.

AU - Nicol, T. L.

AU - Royal, W.

AU - Chin, B. B.

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AB - We describe a patient with AIDS who presented with focal neurological symptoms, and who had contrast-enhancing brain lesions on MRI which demonstrated increased thallium-201 uptake on SPECT. These findings were consistent with lymphoma; however, brain biopsy established a diagnosis of progressive multifocal leukoencephalopathy (PML). To our knowledge, this is the first reported case of PML with increased thallium-201 uptake on brain SPECT.

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KW - Magnetic resonance imaging

KW - Progressive multifocal leukoencephalopathy

KW - Single-photon emission tomography

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Progressive multifocal leukoencephalopathy demonstrating contrast enhancement on MRI and uptake of thallium-201: A case report

Abstract

Keywords

ASJC Scopus subject areas

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