Primary sclerosing cholangitis: Current and future management strategies

John E. Eaton, Jayant A. Talwalkar

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease. The etiology of this disorder is unknown and there are no effective medical therapies. PSC is associated with inflammatory bowel disease and an increased risk for hepatobiliary and colorectal malignancies. The aim of this review is to highlight the clinical features and diagnostic approach to patients with suspected PSC, characterize associated comorbidities, review screening strategies for PSC associated malignancies and review contemporary and future therapies.

Original languageEnglish (US)
Pages (from-to)28-36
Number of pages9
JournalCurrent Hepatitis Reports
Issue number1
StatePublished - Mar 2013


  • Diagnosis
  • Management
  • Primary sclerosing cholangitis

ASJC Scopus subject areas

  • Hepatology
  • Virology


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