Primary aldosteronism. Diagnostic evaluation

W. F. Young, G. G. Klee

Research output: Contribution to journalReview articlepeer-review

161 Scopus citations


For conceptual and practical purposes, the diagnostic approach to primary aldosteronism is divided into two series of studies. First, the diagnosis of primary aldosteronism must be confirmed by demonstrating hypokalemia with inappropriate kaluresis, unsuppressible urine or plasma aldosterone levels, low PRA, and normal glucocorticoid excretion. The second series of studies guides the therapeutic approach by distinguishing APA from IHA. No single test or imaging method has proved to be 100 per cent accurate, and the differentiation between APA and IHA requires a combination of studies.

Original languageEnglish (US)
Pages (from-to)367-395
Number of pages29
JournalEndocrinology and Metabolism Clinics of North America
Issue number2
StatePublished - 1988

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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