Prevalence and types of sleep disturbances acutely after traumatic brain injury

Vani Rao, Jennifer Spiro, Sandeep Vaishnavi, Pramit Rastogi, Michelle Mielke, Kathy Noll, Edward Cornwell, David Schretlen, Michael Makley

Research output: Contribution to journalArticlepeer-review

79 Scopus citations


Primary objective: To assess the prevalence of and risk factors for sleep disturbances in the acute post-traumatic brain injury (TBI) period. Research design: Longitudinal, observational study. Methods and procedures: Fifty-four first time closed-head injury patients were recruited and evaluated within 3 months after injury. Pre-injury and post-injury sleep disturbances were compared on the Medical Outcome Scale for Sleep. The subjects were also assessed on anxiety, depression, medical comorbidity and severity of TBI. Main outcomes and results: Subjects were worse on most sleep measures after TBI compared to before TBI. Anxiety disorder secondary to TBI was the most consistent significant risk factor to be associated with worsening sleep status. Conclusions: Anxiety is associated with sleep disturbances after TBI. Further studies need to be done to evaluate if this is a causal relationship.

Original languageEnglish (US)
Pages (from-to)381-386
Number of pages6
JournalBrain Injury
Issue number5
StatePublished - May 2008


  • Mood disorder
  • Sleep
  • Trauma

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Developmental and Educational Psychology
  • Clinical Neurology


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