Prenatal compensatory renal growth: Documentation with US

Katrina N. Glazebrook, Frank P. McGrath, Brian T. Steele

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


PURPOSE: To determine whether compensatory renal growth (CRG), which occurs in adults, children, and infants after loss of functioning renal tissue, occurs in fetal life. MATERIALS AND METHODS: Prenatal ultrasound scans were used to select 29 patients with a unilateral multicystic dysplastic kidney and four patients with unilateral renal agenesis. Accurate measurements of prenatal renal length were obtained in 21 of these patients; an accurate measurement of postnatal renal length and birth weight was obtained in 27 of these patients. Prenatal and postnatal renal measurements of the contralateral kidney were compared with renal length in 23 matched control patients and previously reported normal renal lengths. RESULTS: The single functioning kidneys in the study patients were significantly longer than those in the control patients before and after birth (P = .001). CONCLUSION: This study provides strong evidence to support the belief that CRG occurs before birth.

Original languageEnglish (US)
Pages (from-to)733-735
Number of pages3
Issue number3
StatePublished - Dec 1993


  • Fetus, genitourinary system, 811.144, 811.869
  • Fetus, growth and development, 811.144, 811.869
  • Kidney, dysplasia, 811.144
  • Kidney, size, 811.144, 811.869
  • Ultrasound (US), in infants and children

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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