Objective: Determine the performance of an interferon-γ release assay in a health care occupational surveillance program. Methods: From January 11, 2005, through January 31, 2006, all new employees (n = 652) undergoing standard, preemployment evaluation at Mayo Clinic, Rochester, Minnesota were evaluated for tuberculosis using a standard process of symptom screening combined with tuberculin skin test (TST) and QuantiFERON-TB Gold test (QFT-G). Results: Comparing the results of QFT-G directly to TST, QFTG showed an overall agreement of 92.5%. Conclusions: False-positive TST were themost significant issue affecting agreement, and in a low-tuberculosis prevalence population, the need for an effective strategy offering low falsepositive results may be best met by combining the TST with QFT-G.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of occupational and environmental medicine|
|State||Published - Mar 2011|
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health