Preeclampsia and Eclampsia: Nephrologist Perspective

Andrea G. Kattah, Vesna D. Garovic

Research output: Chapter in Book/Report/Conference proceedingChapter


Preeclampsia is a heterogenous, systemic disorder that is caused by maternal and placental factors. Preexisting renal disease and chronic hypertension are significant risk factors for the development of preeclampsia, and the degree of renal insufficiency prior to pregnancy is an important determinant of the risk of maternal complications in pregnancy. While pregnancy itself may accelerate renal decline in some patients, it is not clear whether preeclampsia contributes additional damage. There are currently no clinically used biomarkers that can differentiate preeclampsia from intrinsic renal disease, and an interdisciplinary care approach is the best way to help manage these complex cases. There is evidence that preeclampsia is associated with the future low but increased risk of maternal renal disease. It is still unclear whether it is truly an independent risk factor, but preeclampsia may still identify women early in life who are at future risk of developing renal disease. The optimal long-term follow-up of women with preeclampsia is still not known, but providers should appreciate the significant overlap of renal disease and preeclampsia and have a high index of suspicion in women who do not follow a typical clinical course.

Original languageEnglish (US)
Title of host publicationObstetric and Gynecologic Nephrology
Subtitle of host publicationWomen’s Health Issues in the Patient with Kidney Disease
PublisherSpringer International Publishing
Number of pages18
ISBN (Electronic)9783030253240
ISBN (Print)9783030253233
StatePublished - Jan 1 2019


  • Chronic kidney disease and preeclampsia
  • Eclampsia
  • Nephrology and preeclampsia
  • Preeclampsia
  • Pregnancy preeclampsia

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'Preeclampsia and Eclampsia: Nephrologist Perspective'. Together they form a unique fingerprint.

Cite this