Preclinical Bone Repair Models in Regenerative Medicine

Elvis L. Francois, Michael J. Yaszemski

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter provides an overview of current trends in bone tissue engineering (BTE) in regenerative medicine. In the setting of giving a broad overview of BTE, the chapter focuses on the building blocks of bone regeneration in BTE: cells, growth/differentiation factors and scaffolds. The chapter will focus on both in vitro and in vivo bone regeneration preclinical models that are used in BTE. Finally, the chapter discusses selection criteria for choosing an appropriate animal model for in vivo studies.

Original languageEnglish (US)
Title of host publicationPrinciples of Regenerative Medicine
Number of pages7
ISBN (Electronic)9780128098806
ISBN (Print)9780128098936
StatePublished - Jan 1 2018


  • Animal testing
  • Bone regeneration models
  • Bone tissue engineering
  • Regenerative medicine
  • Scaffolds

ASJC Scopus subject areas

  • General Medicine


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