Polyneuropathy in hypereosinophilic syndrome

S. Monaco, B. Lucci, N. Laperchia, F. Tezzon, B. Currò-Dossi, E. Nardelli, C. Giannini, N. Rizzuto

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


We investigated two patients with the idiopathic hyper-eosinophilic syndrome and peripheral neuropathy. Clinical, EMG, and pathological findings were consistent with axonal polyneuropathy. Morphologic changes of the nerve biopsies suggested axonal damage secondary to increased endoneurial pressure from leakage of capillaries. We postulate that endothelial cell damage, followed by nerve edema, is the first step in the pathogenesis of peripheral neuropathy in these patients.

Original languageEnglish (US)
Pages (from-to)494-496
Number of pages3
Issue number3
StatePublished - Mar 1988

ASJC Scopus subject areas

  • Clinical Neurology


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