Uma Thanarajasingam, Floranne Ernste

Research output: Chapter in Book/Report/Conference proceedingChapter


Polymyositis (PM) is an inflammatory myopathy characterized by -symmetric proximal muscle weakness with CD8+ T cells invading non-necrotic muscle fibers. Myositis-specific antibodies may serve as markers of clinical phenotype and treatment response. Statin use has been associated with precipitating an immune-mediated, necrotizing myositis. Herein, we present two cases that were challenging in diagnosis, treatment, and follow-up.

Original languageEnglish (US)
Title of host publicationChallenging Cases in Rheumatology and Diseases of the Immune System
PublisherSpringer New York
Number of pages14
ISBN (Electronic)9781461450887
ISBN (Print)146145087X, 9781461450870
StatePublished - Mar 1 2014


  • Idiopathic inflammatory myopathies
  • Myositis-specific autoantibodies
  • Polymyositis
  • Statin-induced myositis

ASJC Scopus subject areas

  • General Medicine


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