Polymyositis

Uma Thanarajasingam; Floranne Ernste

doi:10.1007/978-1-4614-5088-7_9

Polymyositis

Uma Thanarajasingam, Floranne Ernste

Rheumatology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Polymyositis (PM) is an inflammatory myopathy characterized by -symmetric proximal muscle weakness with CD8+ T cells invading non-necrotic muscle fibers. Myositis-specific antibodies may serve as markers of clinical phenotype and treatment response. Statin use has been associated with precipitating an immune-mediated, necrotizing myositis. Herein, we present two cases that were challenging in diagnosis, treatment, and follow-up.

Original language	English (US)
Title of host publication	Challenging Cases in Rheumatology and Diseases of the Immune System
Publisher	Springer New York
Pages	141-154
Number of pages	14
ISBN (Electronic)	9781461450887
ISBN (Print)	146145087X, 9781461450870
DOIs	https://doi.org/10.1007/978-1-4614-5088-7_9
State	Published - Mar 1 2014

Keywords

Idiopathic inflammatory myopathies
Myositis-specific autoantibodies
Polymyositis
Statin-induced myositis

ASJC Scopus subject areas

General Medicine

Access to Document

10.1007/978-1-4614-5088-7_9

Cite this

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abstract = "Polymyositis (PM) is an inflammatory myopathy characterized by -symmetric proximal muscle weakness with CD8+ T cells invading non-necrotic muscle fibers. Myositis-specific antibodies may serve as markers of clinical phenotype and treatment response. Statin use has been associated with precipitating an immune-mediated, necrotizing myositis. Herein, we present two cases that were challenging in diagnosis, treatment, and follow-up.",

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author = "Uma Thanarajasingam and Floranne Ernste",

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AU - Ernste, Floranne

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AB - Polymyositis (PM) is an inflammatory myopathy characterized by -symmetric proximal muscle weakness with CD8+ T cells invading non-necrotic muscle fibers. Myositis-specific antibodies may serve as markers of clinical phenotype and treatment response. Statin use has been associated with precipitating an immune-mediated, necrotizing myositis. Herein, we present two cases that were challenging in diagnosis, treatment, and follow-up.

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KW - Myositis-specific autoantibodies

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KW - Statin-induced myositis

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M3 - Chapter

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BT - Challenging Cases in Rheumatology and Diseases of the Immune System

PB - Springer New York

ER -

Polymyositis

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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