Plasma brain natriuretic peptide in obstructive sleep apnea

Anna Svatikova, Abu S. Shamsuzzaman, Robert Wolk, Bradley G. Phillips, Lyle J. Olson, Virend K. Somers

Research output: Contribution to journalArticlepeer-review

53 Scopus citations


We compared brain natriuretic peptide (BNP) levels in patients with obstructive sleep apnea (OSA) with and without cardiovascular disease to BNP in healthy control subjects. OSA was not associated with increased plasma BNP or atrial natriuretic peptide (ANP) in otherwise healthy subjects during wakefulness. Untreated OSA increased ANP overnight, and ANP levels decreased with treatment of OSA. However, OSA did not elicit acute overnight changes in BNP, either in normal subjects or in patients with coexisting cardiovascular disease (including chronic heart failure).

Original languageEnglish (US)
Pages (from-to)529-532
Number of pages4
JournalAmerican Journal of Cardiology
Issue number4
StatePublished - Aug 15 2004

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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