PET/MRI: Where might it replace PET/CT?

Eric C. Ehman, Geoffrey B. Johnson, Javier E. Villanueva-Meyer, Soonmee Cha, Andrew Palmera Leynes, Peder Eric Zufall Larson, Thomas A. Hope

Research output: Contribution to journalReview articlepeer-review

76 Scopus citations


Simultaneous positron emission tomography and MRI (PET/MRI) is a technology that combines the anatomic and quantitative strengths of MR imaging with physiologic information obtained from PET. PET and computed tomography (PET/CT) performed in a single scanning session is an established technology already in widespread and accepted use worldwide. Given the higher cost and complexity of operating and interpreting the studies obtained on a PET/MRI system, there has been question as to which patients would benefit most from imaging with PET/MRI versus PET/CT. In this article, we compare PET/MRI with PET/CT, detail the applications for which PET/MRI has shown promise and discuss impediments to future adoption. It is our hope that future work will prove the benefit of PET/MRI to specific groups of patients, initially those in which PET/CT and MRI are already performed, leveraging simultaneity and allowing for greater degrees of multiparametric evaluation. Level of Evidence: 5. Technical Efficacy: Stage 5. J. Magn. Reson. Imaging 2017;46:1247–1262.

Original languageEnglish (US)
Pages (from-to)1247-1262
Number of pages16
JournalJournal of Magnetic Resonance Imaging
Issue number5
StatePublished - Nov 2017


  • CT
  • MRI
  • PET
  • PET/CT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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